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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC2
All Species:
32.73
Human Site:
S1253
Identified Species:
55.38
UniProt:
Q8NI27
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI27
NP_001075019.1
1593
182775
S1253
S
T
T
P
K
G
N
S
S
N
G
N
S
G
S
Chimpanzee
Pan troglodytes
XP_001139291
1595
183045
S1255
S
T
T
P
K
G
N
S
S
N
G
N
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001086217
1593
182783
S1253
S
T
T
P
K
G
N
S
S
N
G
N
S
G
S
Dog
Lupus familis
XP_538164
1593
182721
S1253
S
A
A
P
K
G
N
S
S
N
G
N
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
B1AZI6
1594
182755
S1253
S
T
T
P
K
G
N
S
S
N
G
N
S
G
S
Rat
Rattus norvegicus
XP_233081
1594
182711
S1253
S
T
T
P
K
G
N
S
S
N
G
N
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510761
1648
188085
T1306
S
A
T
P
K
V
T
T
S
N
G
N
S
A
S
Chicken
Gallus gallus
XP_420332
1593
182430
T1252
N
A
T
P
K
V
T
T
S
N
G
N
S
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001003847
1504
172218
T1195
N
I
G
K
T
S
T
T
T
A
A
S
A
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722763
1641
188490
A1315
S
V
I
K
E
P
D
A
K
A
A
S
T
T
R
Honey Bee
Apis mellifera
XP_393587
1354
156054
E1046
E
K
A
I
F
D
K
E
C
S
N
Y
P
G
F
Nematode Worm
Caenorhab. elegans
NP_498392
1437
164369
F1103
M
T
K
L
T
S
G
F
P
V
I
S
H
A
V
Sea Urchin
Strong. purpuratus
XP_795489
1592
178912
S1252
S
K
S
S
N
R
D
S
S
S
A
K
S
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173871
1804
205705
K1296
K
S
D
Q
G
H
L
K
S
K
G
G
N
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
99.9
99
N.A.
97.4
97.4
N.A.
85.8
88.1
N.A.
72.9
N.A.
39.7
43.1
29.5
48.7
Protein Similarity:
100
99.3
100
99.3
N.A.
98.9
99
N.A.
91.4
93.9
N.A.
83.4
N.A.
59
60.2
48.5
65.1
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
66.6
60
N.A.
6.6
N.A.
6.6
6.6
6.6
33.3
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
73.3
73.3
N.A.
40
N.A.
40
13.3
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
15
0
0
0
0
8
0
15
22
0
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
15
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
8
43
8
0
0
0
65
8
0
50
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
8
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
8
15
8
15
58
0
8
8
8
8
0
8
0
0
8
% K
% Leu:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
8
0
43
0
0
58
8
58
8
0
0
% N
% Pro:
0
0
0
58
0
8
0
0
8
0
0
0
8
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
65
8
8
8
0
15
0
50
72
15
0
22
65
15
65
% S
% Thr:
0
43
50
0
15
0
22
22
8
0
0
0
8
8
0
% T
% Val:
0
8
0
0
0
15
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _